The Missouri School for the Blind residential program provides housing for students who are Missouri residents that are unable to be transported to and from school on a daily basis. All dormitories are staffed with residential advisor's who provide assistance to each student based on individual needs.

The residential program has been designed to complement the education program, with an emphasis on those activities normally learned within the students’ home environment. Some of these lifelong skills include personal care, activities of daily living, the development of socialization skills as well as leisure and recreational opportunities.